Custom Post Type on Homepage – Studiopress Genesis Framework

For displaying posts from a custom post type you can use a wp_query() object. In your case this is what you want :

<?php
    $arg = array(
            'post_type' => 'guide', // this can be an array : array('guide','guide1',...)
            'posts_per_page' => 10,
            'order' => 'DESC',
            // 'category_name' => 6
            'post_status' => 'publish'
            );
    $query = new WP_Query($arg);
    if ( $query->have_posts() ) : 
        while ( $query->have_posts() ) : $query->the_post(); 
        ?>
            <article>
                <h2><a href="https://wordpress.stackexchange.com/questions/90978/<?php the_permalink(); ?>" title="<?php the_title(); ?>"><?php the_title(); ?></a></h2>
                <div><?php the_excerpt(); ?></div>
            </article>
        <?php
        endwhile;
    endif;
    wp_reset_query(); 
?>