How to add a Variable to post query

I’m not sure if is this that you need, but try to “explode” it…

<?php 
    // Headlines variable can control admin area

    // Does this return the string "2,3,4,5" ???
    $headlines = get_option('t_turmanset');

    query_posts( array( 'numberposts' => 4, 'post__in' => explode(",", $headlines) ) );
    if ( have_posts() ) : while ( have_posts() ) : the_post(); 
?>