You can handle this by define DATEDIFF()
in SELECT
For example:
SELECT RECID, DATEDIFF(t1.qr_enddate, NOW()) AS diffORD
FROM `mytablw` t1
ORDER BY diffORD ASC;
This should work but in your case I strongly recommend to use wordpress default Filter API posts orderby. This filter is applied before a post-retrieving SQL statement is executed. Use it to make custom modifications to the orderby.