per blog metadata for plugin

Options are site specific, so you just need to use update_option() and get_option().

The network-wide equivalents are update_network_option() and get_network_option(). Note that update_site_option() is just a wrapper for update_network_option(), and is an older name from when a multisite network was (confusingly) called a ‘site’. The same applies for get_site_option().