$query = new WP_Query( $args );
if ( $query->have_posts( $query->have_posts()) ) : while( $query->have_posts()) :
$query->the_post();
global $post;
switch ( $query->current_post ) {
case 0 :
// first post object is in var $post;
echo 'The first post title is ' . $post->post_title;
break;
case 1 :
// because we are insed the loop we can use all the post template tags
echo 'The second post title is ' . get_the_title();
break;
....
}
endwhile; endif;
wp_reset_postdata();