There is no way, at least to my knowledge to unset an option from the screen options panel without unsetting the actual metabox itself.
My suggestion would be to target these screen options item via your CSS and hide it from view.
Add this to your plugin or functions file. Don’t forget to update ‘METABOXIDNAME’ with the ID name of your metabox.
add_action( 'admin_head', 'remove_wordpress_cfields' );
function remove_wordpress_cfields() {
echo '<style>label[for=METABOXIDNAME-hide] { display: none; }</style>';
}
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