i got the same problems several times ago, and it’s caused by file permission in linux.
for make sure about the problems, would you like to show us about the errors by adding below code in your wp-config.php
define( 'WP_DEBUG', true );
define( 'WP_DEBUG_LOG', true );
define( 'WP_DEBUG_DISPLAY', true );
be better if you give web console message to when you clicked the save button.