No, there’s no direct not operator. At least not the way you hope for.
You can use a zero-width negative lookahead, however:
\((?!2001)[0-9a-zA-z _\.\-:]*\)
The (?!...) part means “only match if the text following (hence: lookahead) this doesn’t (hence: negative) match this. But it doesn’t actually consume the characters it matches (hence: zero-width).
There are actually 4 combinations of lookarounds with 2 axes:
- lookbehind / lookahead : specifies if the characters before or after the point are considered
- positive / negative : specifies if the characters must match or must not match.