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Find all the boost libraries (where exefile is the name of your executable): and for each libboost_xxx.dylib, do: and finally verify using otool again: Manpages: otool install_name_tool EDIT A while back I wrote a python script (copy_dylibs.py) to work out all this stuff automatically when building an app. It will package up all libraries from /usr/local or /opt/local into the app bundle and fix references to those … Read more