It is definitely possible. We may need more info though. Do you know how to use page templates? Copy your single.php (or your page.php) from your theme and name it single-your-cpt-slug.php. (Replace ‘your-cpt-slug’ with your actual cpt slug). Within this file remove the call to the featured image. This is a pretty generic answer without knowing more about your setup or what your code looks like.
