@Tal,
Generally speaking you should only be using one caching plugin. WP Super Cache, W3 Total Cache, Hyper Cache and DB Cache Reloaded all drop files directly in your wp-content directory and they would conflict with each other and cause errors if you were using more than one.
I would recommend using W3 Total Cache because it gives you the option of using 5 levels of caching. Page Cache, DB Cache, Object Cache, Minify, and Browser Cache plus it has built in support for using a CDN.
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