You can add custom class to post thumbnails. the_post_thumbnail accepts array of attribute $attr
where you can specify image class.
So your code will be.
<div class="home-featured-img">
<?php
if ( has_post_thumbnail() ) { // check if the post has a Post Thumbnail assigned to it.
the_post_thumbnail( 'full', array( 'class' => 'responsive-class' ) ); // show featured image
}
?>
</div>
In above code, responsive-class
is the custom class I have added, you can change it as you require.