Disable wordpress pagination URL rewrite for specific page

The redirect_canonical filter is responsible for this, which you can selectively disable depending on the requested page. This is untested, but should work:

function wpa66273_disable_canonical_redirect( $query ) {
    if( 'design-jobs' == $query->query_vars['pagename'] )
        remove_filter( 'template_redirect', 'redirect_canonical' );
}
add_action( 'parse_query', 'wpa66273_disable_canonical_redirect' );