wordpress upgrade from 4.2.1 to 4.7.3 500 error

It is hard to track down the cause of a 500 error, so here’s what I’d try:

  1. Be sure to also copy the new root folder files (except wp-config.php) – not just the wp-admin and wp-includes directories.

  2. Go the other way around. Make a backup copy of the current wp-content directory and your wp-config.php file. Do a complete fresh install of the WordPress files from the latest zip and then copy the wp-config.php to the install root and copy the wp-content folder over the new one.