The short answer is yes. But it seems that the WordPress team are moving toward encouraging the creation of networks of sites rather than simply using Multisite. I watched this video:
http://wordpress.tv/2014/07/26/john-james-jacoby-multisite-and-multi-network/
Which gives a good insight into creating a Network of sites. Each Network can have a different domain.
I’m therefore going to install WP Multi Network
A slightly longer answer is yes and no. Once you have created a new site in a subdomain (in my use case) you can then go and edit the site and change the domain completely. Checkout the video for more details on what is going under the hood in the wp_site
, wp_blogs
and wp_sitemeta
tables
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