Duplicate (or more) custom fields on many posts. Is there an easy way to clean them up?

If you’re not going to use those plugins, have at it. No reason to keep them around. Direct SQL query should be fine.

Related: add_post_meta() has a nifty argument to prevent this very problem. The fourth argument is a boolean, declaring whether the meta should be singular:

add_post_meta( $post->ID, 'my_foo_bar', 'value', true );

Source: Add Post Meta | WP Codex

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