Getting rid of the blog page entirely

The Genesis Framework is not for free, so I can’t inspect the code. But I can use Google or any other search engine and found something with custom post types. And as I see the comment // any wp_query() args, I guess you can pass the same arguemnts to the Genesis loop as to the normal wp_query (especially the part with ‘Multiple Posts/Pages Handling’).

function custom_do_cat_loop() {
  global $query_args; // any wp_query() args
  $per_page = 10;
  $args= array(
    'post_type' => 'post',
    'posts_per_page' => $per_page,
    'paged' => get_query_var( 'paged' )
  );
  genesis_custom_loop( wp_parse_args( $query_args, $args ) );
}

This solution is a shot in the dark, but maybe it help you to find more informations on the web.