you should check out the other posts related to this. A lot of times you will have some type of malware in WordPress coded in PHP which screws with your JS codes. I have seen other threads on stack about similar points.. JavaScript widgets do not move and no ajax edits.
Check out this stack thread and also you should clear out any junk files you find inside your theme folder. Or really anything suspicious inside the /wp-includes/ and /wp-content/ directories.
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