You’re trying to delete an open file, and the docs for os.remove() state…
On Windows, attempting to remove a file that is in use causes an exception to be raised
You could change the code to…
filename = os.path.expanduser('~') + '\Desktop\input.txt'
try:
os.remove(filename)
except OSError:
pass
f1 = open(filename, 'a')
…or you can replace all that with…
f1 = open(os.path.expanduser('~') + '\Desktop\input.txt', 'w')
…which will truncate the file to zero length before opening.
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