How to disable single post view in wp

You can add to the end of theme’s header.php file this:

if( is_single() ) {
  global $wp_query;
  $wp_query->set_404();
  status_header( 404 );
  get_template_part( '404' );
  exit();
}

Note that the get_template_part( '404' ) function needs 404.php file in your theme directory.

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