- Error 500 ISE is very generic and can be caused by numerous underlying issues. Your first step should be locating error log for your hosting account or asking support to help with that.
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It may indicate .htaccess issue. Regenerate .htaccess, and be sure the encoding in your text editor is Unicode No BOM
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It may also indicate a problem with the configuration on the server. Usually your hosting company tech support can help.
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