How to Execute a Python Script in Notepad++?

First option: (Easiest, recommended)

Open Notepad++. On the menu go to: Run -> Run.. (F5). Type in:

C:\Python26\python.exe "$(FULL_CURRENT_PATH)"

Now, instead of pressing run, press save to create a shortcut for it.

Notes

• If you have Python 3.1: type in Python31 instead of Python26
• Add -i if you want the command line window to stay open after the script has finished

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Second option

Use a batch script that runs the Python script and then create a shortcut to that from Notepad++.

As explained here: http://it-ride.blogspot.com/2009/08/notepad-and-python.html

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Third option: (Not safe)

The code opens “HKEY_CURRENT_USER\Software\Python\PythonCore”, if the key exists it will get the path from the first child key of this key.

Check if this key exists, and if does not, you could try creating it.