Migrate single site to Multisites with plugins, cPanel and already working subdomains

1) No data/settings/options are lost, very rarely deleted, when deactivating plugins.

2) You do not need a wildcard subdomain unless you want to let visitors register for/create their own site/blog. But it doesn’t hurt to have it. Else: explicitly add all subdomains in zone file.

3) In case you want several domains to map to the same site (special cases) you need Domain Mapping plugin. WP Multisite does not need domain mapping to respond to different domains for each site. (This is a common misunderstanding, though.)

All sudomains that shall be served by the multisite must point to the same root folder as WP is installed in. Use “subdomain install” in WP-config for both subdomains and separate domains.