If the first character is an integer, it will not capitalize the first letter.
>>> '2s'.capitalize()
'2s'
If you want the functionality, strip off the digits, you can use '2'.isdigit() to check for each character.
>>> s = '123sa'
>>> for i, c in enumerate(s):
... if not c.isdigit():
... break
...
>>> s[:i] + s[i:].capitalize()
'123Sa'
