You don’t need to use 4 spaces on your second conditional line. Maybe use:
if (cond1 == 'val1' and cond2 == 'val2' and cond3 == 'val3' and cond4 == 'val4'): do_something
Also, don’t forget the whitespace is more flexible than you might think:
if ( cond1 == 'val1' and cond2 == 'val2' and cond3 == 'val3' and cond4 == 'val4' ): do_something if (cond1 == 'val1' and cond2 == 'val2' and cond3 == 'val3' and cond4 == 'val4'): do_something
Both of those are fairly ugly though.
Maybe lose the brackets (the Style Guide discourages this though)?
if cond1 == 'val1' and cond2 == 'val2' and \ cond3 == 'val3' and cond4 == 'val4': do_something
This at least gives you some differentiation.
Or even:
if cond1 == 'val1' and cond2 == 'val2' and \ cond3 == 'val3' and \ cond4 == 'val4': do_something
I think I prefer:
if cond1 == 'val1' and \ cond2 == 'val2' and \ cond3 == 'val3' and \ cond4 == 'val4': do_something
Here’s the Style Guide, which (since 2010) recommends using brackets.