Never use .onclick(), or similar attributes from a userscript! (It’s also poor practice in a regular web page).

The reason is that userscripts operate in a sandbox (“isolated world”), and onclick operates in the target-page scope and cannot see any functions your script creates.

Always use addEventListener()^Doc (or an equivalent library function, like jQuery .on()).

So instead of code like:

something.outerHTML += '<input onclick="resetEmotes()" id="btnsave" ...>'

You would use:

something.outerHTML += '<input id="btnsave" ...>'

document.getElementById ("btnsave").addEventListener ("click", resetEmotes, false);

---

For the loop, you can’t pass data to an event listener like that See the doc. Plus every time you change innerHTML like that, you destroy the previous event listeners!

Without refactoring your code much, you can pass data with data attributes. So use code like this:

for (i = 0; i < EmoteURLLines.length; i++) {
    if (checkIMG (EmoteURLLines[i])) {
        localStorage.setItem ("nameEmotes", JSON.stringify (EmoteNameLines));
        localStorage.setItem ("urlEmotes", JSON.stringify (EmoteURLLines));
        localStorage.setItem ("usageEmotes", JSON.stringify (EmoteUsageLines));
        if (i == 0) {
            console.log (resetSlot ());
        }
        emoteTab[2].innerHTML  += '<span style="cursor:pointer;" id="' 
                                + EmoteNameLines[i] 
                                + '" data-usage="' + EmoteUsageLines[i] + '">'
                                + '<img src="' + EmoteURLLines[i] + '" /></span>'
                                ;
    } else {
        alert ("The maximum emote (" + EmoteNameLines[i] + ") size is (36x36)");
    }
}
//-- Only add events when innerHTML overwrites are done.
var targetSpans = emoteTab[2].querySelectorAll ("span[data-usage]");
for (var J in targetSpans) {
    targetSpans[J].addEventListener ("click", appendEmote, false);
}

Where appendEmote is like:

function appendEmote (zEvent) {
    //-- this and the parameter are special in event handlers.  see the linked doc.
    var emoteUsage  = this.getAttribute ("data-usage");
    shoutdata.value += emoteUsage;
}

WARNINGS:

• Your code reuses the same id for several elements. Don’t do this, it’s invalid. A given ID should occur only once per page.
• Every time you use .outerHTML or .innerHTML, you trash any event handlers on the affected nodes. If you use this method beware of that fact.