Update a WordPress post or page takes 60+ seconds

There’s a plugin called Debug Bar which you can find at http://wordpress.org/plugins/debug-bar/ Don’t leave this enabled in production! But it will tattle on slow MySQL queries.

You might also wish to try using WP Clean Up. http://wordpress.org/plugins/wp-clean-up/ This flushes out stale entries in your database, and does a little bit of table reorg/optimization.