What is the best way to correlate one-to-many content-type relationships?

I think perhaps an Available Space Custom Post Type, along with custom post metadata for the Available Space CPT, to correlate each Available Space CPT with its appropriate Building CPT, is the way to go here.

A one-to-one relationship would lend itself well to custom post metadata in the Building CPT itself, but the one-to-many relationship really implies that you should go the CPT route.