It appears to be a bug, but one that can be hacked around each time it happens with about 2 seconds of work. This wordpress forum thread:
If you’re using Chrome, right-click on the greyed-out “Update” button
and select “Inspect Element”. You will see something to the likes of:
<input name="save" type="submit" class="button button-primary
button-large disabled" id="publish" accesskey="p" value="Update">Just delete the word
disabled
and the update button will become
clickable again. Click it and it should update.Saved me reloading and losing work.
See also this less resolved thread.
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